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Senior Medical Director, Clinical Development

Posted date Jun. 12, 2025
Contract type Full time
Job ID R-228437
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Why choose AstraZeneca Spain?

AstraZeneca Spain is a rising force in our global business. With headquarters in Madrid and our global hub in Barcelona, we’ve become an important international centre of excellence in the fight against critical disease. Boasting vibrant universities and business schools, the Barcelona ecosystem is a place where scientists can thrive. We attract a diverse workforce from across the globe, shining a beacon for innovation in a country that’s committed to clinical development.

We invite you to bring your talents to Barcelona where our respiratory medicine R&D and Global Marketing centre offers opportunities in R&D, IT, Commercial and HR. Or join us in Madrid and shape our growth in our BUs (Respiratory, Oncology & CVRM ), and a range of Corporate functions. Additionally, you can find sales roles throughout the country. Together, we’re contributing to a world-leading pipeline of therapeutics and delivering life-changing medicines to patients.

Who do we look for?

Calling all tech innovators, ownership takers, challenge seekers and proactive collaborators. At AstraZeneca Spain, breakthroughs born in the lab become transformative medicine for the world's most complex diseases. Alongside technical expertise, colleagues have the resilience, energy and collaborative mindset to change lanes, work with different teams and start projects from scratch.

Here, diverse minds and bold disruptors can meaningfully impact the future of healthcare using cutting-edge technology. Whether you join us in Madrid or Barcelona, you can make a tangible impact within a global biopharmaceutical company that invests in your future. Join a talented global team that's powering AstraZeneca to better serve patients every day.

Success Profile

Ready to make an impact in your career? If you're passionate, growth-orientated and a true team player, we'll help you succeed. Here are some of the skills and capabilities we look for.

Diverse collaborators

This is a speak-up culture that values collaboration. You’ll proactively bring your unique perspectives, experiences and skills to the table and seek the same from others. With our international team composition and the need for fast-paced collaboration, you’ll always be building new connections with colleagues.

Cutting-edge innovators

When you join us, you’ll be part of a team that embraces digital technology and data to transform the way we work and the work we do. Every day, you’ll help make history, empowered to ignite your creativity and build something enduring.

Resilient trailblazers

Here, the answers aren’t always available. So, you’ll need to bring a fearless, self-starter mindset to navigate uncharted territories. You’ll harness your ceaseless energy to discover and make the necessary connections with colleagues to shape the future and achieve maximum impact.

Agile movers

Seize ownership and excel with autonomy to enjoy the constant rush of ground-breaking discovery. Your ability to anticipate sudden shifts and adapt swiftly will prove critical as you make your mark in an environment that rewards initiative and resilience.

Responsibilities

Job ID R-228437 Date posted 06/12/2025

Senior Medical Director, Clinical Development

This is what you will do:

As a Senior Medical Director, Clinical Development you will be a key component of the Project Team, working synergistically with the global project team lead and clinical team as the expert in medical scientific aspects of the drug and its development during clinical phase. The nature of this role may require working across projects and diseases.

The key accountabilities will include driving components of or the whole clinical programme strategy for individual projects, as well as the overall concept and design of clinical trials within Alexion, Clinical Development Team. You will also be the scientific leader with regards to the development, interpretation and implementation of new endpoints.

For Alexion, we work across multiple rare diseases in specialities focused on Endocrinology, Neurology, Hematology, Cardiology, Nephrology, Pediatrics and Oncology. We are now looking for a new colleague in the growing disease area covering rare endocrinology, metabolic bone disease and rare oncology.

You will be familiar or become familiar with relevant Regulatory guidelines for drug development for the key Endocrinology and rare bone diseases, as well as current treatment guidelines, relevant competitor trial designs and data as these are continually evolving. As such this will enable you to build novel and innovative approaches cross all phases of Clinical development, including Experimental Medicine studies generating data for Go/NoGo decision making to Phase 3 registrational studies

Additional tasks may include the set-up, design, conduct, reporting and regulatory submission of clinical trials; participation and leadership of cross-functional workstreams within and outside of Alexion. Finally, as a Medical Director you will play a crucial role in leading cross-project activities to direct Rare disease Clinical Development Strategy.

You will be responsible for:

  • Guide clinical science aspects of the Clinical Development Plans (CDP) and Clinical Study Protocols in keeping with the approved CDP and ensuring linkage of trial data to target product claims / profile

  • Lead clinical scientific input to the set-up, design (target population, translational biomarker selection and low reference value/target value characterization for decision making), study analysis planning and reporting as well as regulatory submissions

  • Initiate and support key contacts with opinion leaders, and help develop alliances as appropriate

  • Write and check content and quality of product related publications and input to development of publication strategy

  • Follow important developments and trends in the clinical & scientific literature to provide value and direct strategy across Rare Disease Clinical Development

You will need to have:

  • Medical Degree with a subspeciality preferably in Internal Medicine, Paediatrics, Endocrinology or Oncology with many years in clinical practice.

  • You have several years of clinical drug development within a pharmaceutical company environment.

  • A good understanding of more than one development function

  • Phenomenal interpersonal skills

  • Excellent verbal and written communication skills in English

  • Ability to acquire and assimilate knowledge in different disciplines, diseases and therapeutic areas

  • Share our values to put patients first, follow the science, do the right thing and play to win

  • A curious and entrepreneurial mindset

If you are ready to make a difference - apply today, and we'll make it happen together!

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

10001120 G CDGE Alexion - AstraZeneca Rare Diseases

Reasons to Join

Thomas Mathisen

There are many things I enjoy when working at AstraZeneca, mainly the Speak up culture, the great colleagues that are in my teams, the great products that AstraZeneca provides to our patients and the challenging conversations I have around our medicines.

Sales Representative Oslo, Norway

There are many things I enjoy when working at AstraZeneca, mainly the Speak up culture, the great colleagues that are in my teams, the great products that AstraZeneca provides to our patients and the challenging conversations I have around our medicines.

Christine Recchio

Working at AstraZeneca has impacted my life in such a positive way. I now have an improved work-life balance through creating my own schedule and time management, I feel a balance that I didn’t have before.

Sales Representative California, United States

Working at AstraZeneca has impacted my life in such a positive way. I now have an improved work-life balance through creating my own schedule and time management, I feel a balance that I didn’t have before.

Stephanie Ling

There are a lot of reasons why I enjoy working in AstraZeneca, my colleagues being one of them. My team members and the managers have provided a great deal of guidance in helping me to be more confident in my daily work.

Sales Representative Petaling Jaya, Malaysia

There are a lot of reasons why I enjoy working in AstraZeneca, my colleagues being one of them. My team members and the managers have provided a great deal of guidance in helping me to be more confident in my daily work.

What we offer

We're driven by our shared values of serving people, society and the planet. Our people make this possible, which is why we prioritise diversity, inclusivity, balance and sustainability. Discover what a career at AstraZeneca could mean for you.

An award-winning company

We're passionate about being a great place to work, and 84% of our employees would recommend us as an employer. We've been recognised as a Top Employer in Spain, an EFR Family Responsible Business, and we achieved third place in Forbes Spain's Top 50 Best Places to Work list.

Inclusive environment

Diversity and inclusion are embedded in everything we do, and our different views, experiences and strengths enrich our culture. There's no salary gap at AstraZeneca, and the number of female employees has increased by four per cent over the last three years. We've also made all positions fully accessible.

Work-life balance

Your wellbeing means a lot to us, and we're here to support you through all of life's ups and downs. That's why we offer an unpaid leave policy, annual leave, reduced-hours timetables and a host of benefits, including a retirement plan, long service award, and health and travel insurance.

Sustainability initiatives

We're committed to harnessing the power of science to become a more sustainable business. We've reduced our carbon footprint by over 9,000 kg of CO2 over the last two years, and we lead the European GoGreen Project, which aims to introduce environmentally friendly options in our fleet of corporate vehicles.

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Great culture, great work assignments, supportive management. Rotation opportunity within the company. They value our people.